Alteration of cerebral perfusion and cortical thickness in depression episodes: a comparative MRI study

Aim: We aimed to determine the difference between cerebral perfusion and cortical thickness first attack recurrent in major depression patients.
 Material Method: Our study was conducted prospectively 01.03.2017-03.03.2018 Izzet Baysal University Psychiatry department. 40 patients (21 episodes 19 episodes) diagnosed with according DSM 5 by American Psychiatric Association a control group of 16 healthy individuals were evaluated for blood flow Perfusion MRI. Patients also Hamilton rating scale.
 Findings: The significantly decreased attacks.There no significant CBF episode episodes, except cingulate cortex, which showed reduced values group. In higher scale points, insular cortex decreased.
 Conclusion: These findings suggests that atrophy activation default mode network leads response treatment.